Renal Pre-Contrast Screening (CT / MRI)
Screening questionnaire to identify patients at higher risk of renal dysfunction (eGFR <45 mL/min/1.73 m²), a level below which the risk of contrast-induced nephropathy (on CT with iodinated contrast) increases significantly. Also effectively stratifies nephrogenic systemic fibrosis (NSF) risk before gadolinium-enhanced MRI, with potential for cost savings and streamlined care. High sensitivity and moderate-to-good specificity; validated for ambulatory use.
Renal Pre-Contrast Screening (CT / MRI)
Answer the 6 questions below. All are required.
Answer all questions to generate the result.
Evidence
In a study of 1361 ambulatory patients, for detecting eGFR <45 mL/min/1.73 m² the questionnaire showed sensitivity of 92.9%, specificity of 65.3%, PPV of 2.7% and NPV of 99.9%. (Too et al., Eur J Radiol 2015)
The questionnaire also effectively stratifies nephrogenic systemic fibrosis (NSF) risk before gadolinium-enhanced MRI, with potential for cost savings and streamlined care. When the decision to administer gadolinium is based solely on questionnaire responses at the time of order, sensitivity of 71.4% for detecting eGFR <30 mL/min/1.73 m², specificity of 74.2%, PPV of 2.9% and NPV of 99.6% were observed. (Choyke et al., Radiology 2003)